This article provides an update of the guidelines for HER2 testing in the UK. It aimed to further improve the analytical validity and clinical utility of HER2 testing by providing guidelines of test performance parameters, and recommendations on the post-analytical interpretation of test results. The authors published these guidelines on behalf of the National Coordinating Committee for Breast Pathology
This article describes the macroscopic handling and reporting of breast cancer specimens pre- and post-neoadjuvant chemotherapy treatment and reviews pathological issues and suggested some practical approaches
In this review article, the authors present an analysis of the validity of histological grade as a prognostic factor and a consensus view on the significance of histological grade and its role in breast cancer classification and staging systems in this era of emerging clinical use of molecular classifiers.
Ki67 Assessment in Breast Cancer
The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014
First International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions) (2016)
This review article provides a consensus view on phyllodes tumours of the breast
UK DCIS review of margins: Breast conservation in ductal carcinoma in situ (DCIS): what defines optimal margins? (2016)
This review aims to address the clinical question of the minimal margin width in DCIS treated with breast conserving surgery (BCS) that is associated with the lowest recurrence rate. A range of clinical circumstances that might affect this are considered.
Sentinel Lymph Node in Breast Cancer: Review Article from a Pathologist’s Point of View (2016) (1), (2), (3)
These articles provide an update of the ASCO Clinical Practice Guideline and a brief history of TNM with a focus on N-stage and innate problems with the guidelines, and why pathologists may have difficulties in assessing lymph node metastases uniformly. It also describes the clinical significance of isolated tumor cells, micrometastasis, and macrometastasis
Latest recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer by the American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline.
American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer.
1-Margins for breast-conserving surgery with whole-breast irradiation in stage I and II invasive breast cancer: American Society of Clinical Oncology endorsement of the Society of Surgical Oncology/American Society for Radiation Oncology consensus guideline (2014).
2-Surgical Options and Locoregional Recurrence in Patients Diagnosed with Invasive Lobular Carcinoma of the Breast (2015)
Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast Conserving Surgery With Whole Breast Irradiation in Ductal Carcinoma In Situ (2016)
Integration of next-generation sequencing in clinical diagnostic molecular pathology laboratories for analysis of solid tumours; an expert opinion on behalf of IQN Path ASBL
1 – Papillary Lesions of the Breast: An Update (2016)
2 – Pathological criteria and practical issues in papillary lesions of the breast – a review (2016)
3 – Papillary lesions of the breast: selected diagnostic and management issues (2008)